Protective Effect of Administrated Glutathione-enriched Saccharomyces cerevisiae FF-8 Against Carbon Tetrachloride (CCl₄)-induced Hepatotoxicity and Oxidative Stress in Rats
2007
Shon, M.Y. (Gyeongsang National University, Jinju, Republic of Korea) | Cha, J.Y. (Daesun Distilling Co., Ltd., Busan, Republic of Korea) | Lee, C.H. (Dong-A University, Busan, Republic of Korea) | Park, S.H. (Dong-A University, Busan, Republic of Korea) | Cho, Y.S. (Dong-A University, Busan, Republic of Korea), E-mail: [email protected]
The present work is aimed to evaluate the protective effect of glutathione-enriched Saccharomyces cerevisiae FF-8 strain on carbon tetrachloride (CCl₄)-induced hepatotoxicity and oxidative stress in rats. The activities of liver markers (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase), lipid peroxidative index (thiobarbituric acid-reactive substances), and the antioxidant status (reduced glutathione) were used to monitor those protective roles of FF-8 strain.
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