Heterophil emperipolesis rabbit haemorrhagic disease
2009
Alexandrov, M., Institute of Experimental Pathology and Parasitology, BAS, Sofia (Bulgaria) | Peshev, R., Bulgarian Academy of Sciences, Sofia (Bulgaria) | Lasarova, S., Institute of Experimental Pathology and Parasitology, BAS, Sofia (Bulgaria) | Doumanova, L., National Diagnostic and Research Veterinary Institute, Sofia (Bulgaria) | Tchorbanov, A., National Diagnostic and Research Veterinary Institute, Sofia (Bulgaria) | Bostandjieva, R., Bulgarian Academy of Sciences, Sofia (Bulgaria)
Liver and spleen obtained from rabbits deceased after inoculation with rabbit haemorrhagic disease virus RHDV were studied by means of light, transmission electron and immunoelectron microscopy. Sever damages located within nuclei and cytoplasma of many periportal hepatocytes and splenic macrophages were detected. Howevwr the most promined pathological lesions were multifocal liver necroses abundantly infiltrated with heterophil granulocytes, as well as heterophils foundthroughout the red pulp of the spleen.
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