Titres of specific antibodies against Toxoplasma gondii in goats and their kids
2009
Misurova, L.,Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Klinika Chorob Prezvykavcu | Svobodova, V.,Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Ustav Parazitologie | Pavlata, L.,Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Klinika Chorob Prezvykavcu | Dvorak, R.,Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Klinika Chorob Prezvykavcu
The aim of our study was to perform repeated determination of specific antibody levels in goats and their kids in order to assess indirectly the possibility of vertical transmission of toxoplasmosis in goats. Twenty-eight goats with their kids were included in the study. The following variables were assessed: number of born kids in relation to antibody titres of goats; levels of specific antibodies in the blood of goats and kids; and concentrations of immunoglobulins (Ig), total protein (TP) and total globulins (G) in order to define the end of colostral immunity and the start of active production of antibodies in kids under 69 days of age. Specific antibodies against Toxoplasma gondii in goats were detected by IFAT in titres ranging from 0 to 1,280. Five goats were negative and 23 goats were seropositive. The goats delivered 42 kids. Negative goats tended to have significantly more kids (ratio 1.80) than positive ones (ratio 1.35). A significant decrease in levels of TP, Ig and G was observed between days 27 and 41. Samples taken on days 55 and 69 proved gradual increase of active production of antibody response, which was supported also by a significant increase of monitored non-specific immunity indicators. During this period, we observed increased titres of specific antibodies against toxoplasmosis in 20 kids (5 kids 41 days old, 5 kids 55 days old, and 10 kids 69 days old) and thus we could assume the possibility of vertical transmission of toxoplasmosis.
显示更多 [+] 显示较少 [-]