Roles of the hypocretin/orexins in the regulation of sleep and wakefulness
2008
Terao, A.(Hokkaido Univ., Sapporo (Japan)) | Haruyama, T. | Kimura, K.
Hypocretin/orexin is produced exclusively in the dorsal and lateral hypothalamus but its projection is widespread within the brain and plays important roles. In this paper, we review the independent discoveries of the hypocretin/orexin peptides, the neuroanatomy of this system, and the link to the sleep disorder narcolepsy that has led to the idea that this system plays a crucial role in the regulation of sleep and wakefulness.
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书目信息
Japanese Journal of Veterinary Research (Japan)
卷
55
期
2-3
ISSN
0047-1917
页码
pp. 75-83
其它主题
Peptidos; Encephale; Systeme nerveux
语言
英语
注释
Summary (En)
72 ref.
类型
Bibliography; Lit. Review; Summary
2009-03-15
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