Hepatoprotective Effect of Fermented Artemisia princeps PAMPANINI by Lactic Acid Bacteria
2007
Choi, H.J. (Kyung Hee University, Seoul, Republic of Korea) | Kim, E.J. (Kyung Hee University, Seoul, Republic of Korea) | Han, M.J. (Kyung Hee University, Seoul, Republic of Korea) | Baek, N.I. (Kyung Hee University, Suwon, Republic of Korea) | Kim, D.H. (Kyung Hee University, Seoul, Republic of Korea) | Jung, H.G. (Ganghwa Agricultural RnD Center, Inchon, Republic of Korea) | Kim, N.J. (Kyung Hee University, Seoul, Republic of Korea), E-mail: [email protected]
Artemisia princeps PAMPANINI has been used in traditional medicine of the treatment of inflammatory, liver dysfunction and order disorder in the far east countries including Korea. The present study was carried out to investigate the hepatoprotective effects of ethanol extract of Artemisia princeps (AP) and its fermented agents (AP-F) by lactic acid bacteria derived from human intestinal bacteria on liver injured rat induced by CCl₄ and d-galactosamine. Hepatoprotective activity was monitored by estimating serum ALT, AST, ALP, LDH, superoxide dismutase (SOD), glutathione redeuctase (GR) and glutathione peroxidase (Gpx) activities in the liver injured by hepatotoxin.
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