Effect of Feed Restriction in Modeling of Dietary Obesity
2007
Cho, Y.M. (Chungbuk National University, Cheongju, Republic of Korea) | Shin, S.H. (Chungbuk National University, Cheongju, Republic of Korea) | Park, D.S. (Chungbuk National University, Cheongju, Republic of Korea) | Jeon, J.H. (Chungbuk National University, Cheongju, Republic of Korea) | Jang, M.J. (Chungbuk National University, Cheongju, Republic of Korea) | Kim, J.J. (Chungbuk National University, Cheongju, Republic of Korea) | Kim, J.W. (Chungbuk National University, Cheongju, Republic of Korea) | Ji, H.J. (Chungbuk National University, Cheongju, Republic of Korea) | Kim, C.H. (Seoul National University, Seoul, Republic of Korea) | Baek, S.J. (Biotoxtech Co., Ltd., Cheongwon, Republic of Korea) | Hwang, S.Y. (Juseong College, Cheongwon, Republic of Korea) | Kim, G.H. (Chungbuk National University, Cheongju, Republic of Korea) | Kim, Y.B. (Chungbuk National University, Cheongju, Republic of Korea), E-mail: [email protected]
Ad libitum feeding of normal diet to rats usually leads to overweight, showing higher body-mass index than 25, while the supplementation of high (20-40%) content of lard or beef tallow in the diet to make a high-fat diet (HFD)-induced obesity rather decreases body weights partially due to decrease in feed intake of HFD or occurrence of diarrhea. In our study, for modeling dietary obesity, rats were subjected to feed restriction by 20 and 40% with normal diet or HFD supplemented with 25% of lard for 6 weeks.
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