Anti-inflammatory activity of methanolic and aqueous extracts of Valeriana wallichii DC Rhizome
2007
Subhan, F. (Peshawar Univ. (Pakistan). Dept. of Pharmacy) | Karim, N. (Peshawar Univ. (Pakistan). Dept. of Pharmacy) | Ibrar, M. (Peshawar Univ. (Pakistan). Dept. of Botany)
Valeriana wallichii DC (Valerianaceae) is an indigenous medicinal plant used in ethno-medicine for the treatment of habitual constipation, insomnia, epilepsy, neurosis, anxiety and as a diuretic, hepatoprotective, analgesic and cytotoxic. The aqueous extract (Aq.Ext) and methanolic extract (Me.Ext) were subjected to anti-inflammatory activity using experimental animal model of carrageenans induced paw oedema in the presence of control for comparison. The results showed that both Aq and Me extracts significantly ameliorate oedema comparable to reference standard, aspirin. The results of this study explicate justification of the use of this plant in the treatment of inflammatory disease conditions.
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