Expression of alfa-SMA, desmin and vimentin in canine liver with fibrosis
2009
Knezevic, M. | Gledic, D. | Kukolj, V., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Knezevic, Dj., Clinical Center of Serbia, Belgrade (Serbia). Institute of Digestive Diseases | Jovanovic, M. | Bozic, T. | Aleksic-Kovacevic, S., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine
In this paper we have described the distribution and localization of cells that express alfa-SMA, desmin, and vimentin in the liver of dogs with various degrees of fibrosis, as well as the significance of HSC and portal myofibroblasts in the genesis of fibrosis. The results obtained suggest that portal myofibroblasts have a significant role in the process of liver fibrosis in dogs.
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