Factors of rabbits blood under eimeriosis and trichostrongylidosis
2008
Khaliullina, O.Kh., Bashkir State Agrarian Univ., Ufa (Russian Federation)
In rabbit growing farms there are cases of mixed invasion. Anti-parasitic measures weaken the immune system in animals. The aim of the study is to investigate the immune status of rabbits under eimeriosis and trichostrongylidosis invasion (ETI) accompanied by chemotherapy. The study involved 4 groups rabbits with spontaneous ETI, 12 heads in each group: group 1 – control, group 2 – sick untreated; group 3 – metrodinasol and albamelin treated sick rabbits; group 4 - metrodinasol and albamelin treated sick rabbits taken simultaneously with probiotic vetelakt; group 5 - metrodinasol and albamelin treated sick rabbits taken simultaneously probiotics erakond. The trial lasted 30 days. The blood was collected before the trial and in 5, 10, 15 and 30 days after administering the preparations. In blood the content of hemoglobin, erythrocytes, leucocytes, total protein, protein fractions, T-lymphocytes, circulating immune complexes (CIC), the number of some immunoglobulins and phagocytic activity of leucocytes (PAL) were determined. The level of hemoglobin in sick rabbits was much lower than in the control. The number of leucocytes in sick rabbits was increased and at day 15 it was normal. The albumin decreased. The number of T-lymphocytes and PAL in sick rabbits was much lower than in the control caused by immunodeficiency. After treatment the level of T-lymphocytes was higher by 44%, and PAL – by 40% higher than in the second group. The probiotics improved these parameters at day 15. The high level of CIC in sick rabbits 30 days after treatment decreased in 3, 4, and 5 groups compared to the 2 group. It is concluded that the combined use of probiotics with metrodinasol and albamelin accelerates recovery from ETI
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