Blood glucose, insulin and inorganic phosphorus in healthy and ketotic dairy cows after intravenous infusion of glucose solution
2009
Djokovic, R.,Cacak Univ. of Kragujevac (Serbia). Dept. of Animal Science | Samanc, H.,University of Belgrade (Serbia). Dept. for Diseases of Ruminants and Pigs | Ilic, Z.,Zubin Potok Univ. of Pristina (Serbia). Dept. of Animal Science | Kurcubic, V.,Cacak Univ. of Kragujevac (Serbia). Dept. of Animal Science
The aim of the present study was to determine the degree of blood glucose utilization by peripheral tissue on the basis of changes in blood concentrations of glucose, insulin and inorganic phosphorus in healthy (n = 10) and ketotic cows (n = 10) after intravenous infusion of glucose solution. Blood samples were taken in both groups of examined cows at the following time intervals: just before (time 0) and 30, 60, 120, 180 and 240 min after intravenous infusion of a total of 500 mL of 50% of glucose solution. Glucose and insulin blood serum values in both groups of cows increased significantly within 30 and 60 min of the experiment. Significantly lower values of insulin in blood serum of ketotic cows in comparison with the healthy ones were established within 30 and 60 min of the test. This indicated that the ability of beta cells of the endocrine pancreas to release insulin is reduced in cows suffering from ketosis. After intravenous infusion of glucose the values of inorganic P decreased in the blood of both groups. Within 180 and 240 min of testing there was a significant decrease in inorganic P concentrations in ketotic cows in comparison with healthy ones. This is linked with the active entry of glucose into the glucolytic pathway of peripheral tissues. It can thus be concluded that there is a higher degree of blood glucose utilization by peripheral tissues in ketotic cows.
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