Survey of extended-spectrum β-lactamase (ESBL) in pathogenic Escherichia coli isolated from poultry in Korea
2008
Sung, M.S. (Kyungpook National University, Daegu, Republic of Korea) | Kim, J.H. (Kyungpook National University, Daegu, Republic of Korea) | Cho, J.K. (Health and Environmental Research Institute, Daegu, Republic of Korea) | Seol, S.Y. (Kyungpook National University School of Medicine, Daegu, Republic of Korea) | Kim, K.S. (Kyungpook National University, Daegu, Republic of Korea), E-mail: kimkiseuk@knu.ac.kr
This study was conducted to investigate incidence of extended-spectrum β-lactamase (ESBL) producing strains and characteristics of ESBL gene in pathogenic Escherichia coli isolated from poultry during the period from April 2003 to December 2005 in Korea. Among 203 isolates, 4 isolates (3 from broilers and 1 from layer) were confirmed as ESBL producing strains by double disk synergy test, polymerase chain reaction and sequencing for β-lactamase genes. bla∧CTX-M-15 and bla∧CMY-2 were detected in these 4 isolates and were transferred to recipient by conjugation, respectively. Also, these ESBL producing strains were associated with multiple drug resistance. In conclusion, these results exhibit incidence of CTX-M and CMY-2 β-lactamase in pathogenic E coli from poultry in Korea, and clinically important meaning in human. And they also suggest the needs for rapid and broad surveillance to monitor ESBL genes and R plasmid transferring resistant gene in poultry.
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