In Vitro Genotoxicity of Wastewaters from the Town of Settat, Morocco
2009
El Asslouj, Jaouad (Laboratory of Environmental Metrology, University Hassan I, FST Settat, Morocco) | Amahdar, Loubna (Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco) | Glouib, Kamal (Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco) | Kholtei, Sanae (Laboratory of Environmental Metrology, University Hassan I, FST Settat, Morocco) | El Amrani Paaza, Namira (Laboratory of Applied Geology, University Hassan I, FST Settat, Morocco) | Verschaeve, Luc (Department of Epidemiology and Toxicology, Scientific Institute of Public Health, Brussels, Belgium) | Hilali, Abderraouf (Research Group on Toxicogenetics and Mutagenesis, Laboratory of Agrofood and Health, University Hassan I, FST Settat, Morocco)
英语. In recent years, the town of Settat has seen a considerable industrial growth, which has resulted in increased environmental pollution. This includes pollution by household and industrial wastewaters, which are released into the Boumoussa River without any preliminary treatment. The river valley crosses the community of Mzamza 8 km to the north of the town. Years of drought forced members of the community to use this polluted ground water for irrigation and put themselves and the environment at risk.The aim of this study was to determine the physicochemical and metal profile of Settat wastewaters and to assess their impact on the water table. The second objective was to investigate the genotoxic potential of wastewater on human peripheral blood lymphocytes in vitro, using the micronucleus test and cellular proliferation index.This study demonstrated significant pollution of Boumoussa valley groundwater and of the local wells. Sampled water induced a clear increase in the frequency of micronucleated cells and a lower cell proliferation in human peripheral blood lymphocytes in vitro.
显示更多 [+] 显示较少 [-]克罗地亚语. Nagli industrijski razvoj u gradu Settatu posljednjih je godina rezultirao povećanim onečišćenjem okoliša, osobito putem otpadnih voda iz kućanstava i industrije. Te se otpadne vode bez ikakve prethodne obrade odlažu u dolinu rijeke Boumoussa na području zajednice Mzamza, 8 km sjeverno od grada. Uzastopne sušne sezone lokalnoj su zajednici nametnule potrebu za uporabom tih voda za navodnjavanje, čime su i zajednica i okoliš postali izloženi povećanim rizicima od onečišćenja tla i izvora podzemnih voda. Svrha ovog istraživanja bila je provesti fizikalno-kemijsku karakterizaciju i utvrđivanje sadržaja metala u otpadnim vodama grada Settata te procijeniti njihove učinke na gornji sloj podzemnih voda. Ujedno je istraživan genotoksični potencijal otpadnih voda u uvjetima in vitro na limfocitima periferne krvi čovjeka primjenom mikronukleusnog testa i proliferacijskog indeksa. Istraživanje je potvrdilo visok stupanj onečišćenja vodâ u dolini Boumoussa, kao i vodâ iz bunara smještenih u neposrednoj blizini. Štetni su učinci onečišćenja potvrđeni i na osnovi povišene učestalosti stanica s mikronukleusima te snižene vrijednosti proliferacijskog indeksa u limfocitima periferne krvi u uvjetima in vitro.
显示更多 [+] 显示较少 [-]