A study on oxidative stress and complete blood count of sheep bred in the area exposed to depleted uranium (DU) ammunition
2009
Jovic, S., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Aleksic, J., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Krstic, A., Institute for Medical Research, Belgrade (Serbia) | Stevanovic, J., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Kovacevic-Filipovic, M., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Borozan, S., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Bozic, T., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Popovic, D., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine
The paper presents the results of several health status parameters of sheep bred in the area exposed to depleted uranium (DU) ammunition during NATO bombing of Serbia and Montenegro in 1999. The blood samples of sheep were collected randomly in the region of Bujanovac (Serbia), in 2004. Complete blood count was performed according to standard laboratory procedures. The results of complete red blood cells count indicated normocytic hypochromic anaemia. Total number of leukocytes and the differential leukocytes count were within the physiological range. Although the leukocytes adhesiveness was not changed in DU exposed animals, their increased NBT reduction revealed stimulated leukocytes oxidative burst. This finding, together with significantly increased RBC MDA (red blood cells malondialdehyde) concentrations, as well as the activity of RBC antioxidant SOD, point to existence of oxidative stress. Although the results indicated that animals were under oxidative stress, still there are no conclusive data that it was due to the exposure of DU that entered the environment during military operations.
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