Electrophoretic and immunoelectrophoretic characteristics of IgG as a constituents of PEG precipitable immune complexes in preruminant calves sera
2010
Fratric, N., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine | Ilic, V., University of Belgrade, Belgrade (Serbia). Institute for Medical Research | Milosevic-Jovcic, N., University of Belgrade, Belgrade (Serbia). Institute for Medical Research | Stojic, V., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine
Electrophoretic and immunoelectrophoretic analysis showed that until one month of age, calves sera and PEG precipitates contained only one part of IgG molecules which corresponded to fast, anionic gamma globulins. Although at the age of one month, preruminant calves sera contained all molecular forms of IgG molecules present in the sera of adult cattle, only one part of serum IgG (fast, anionic IgG) was precipitated by PEG. In older calves, all molecular forms of serum IgG had the capacity to form PEG precipitable immune complexes. Presented data, as well as the results of our previous work, can be used as parameters with reference to physicochemical and immunochemical characteristics of IgG immune complexes of preruminant calves under pathological conditions.
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