The effect of low dose ionizing radiation and cadmium chloride on glucose metabolism in broiler chickens
2010
Danova, D.,Univerzita Veterinarskeho Lekarstva, Kosice (Slovak Republic). Ustav Biologie, Zoologie a Radiobiologie | Kafka, I.,Univerzita Veterinarskeho Lekarstva, Kosice (Slovak Republic). Ustav Biologie, Zoologie a Radiobiologie | Kalenicova, Z.,Univerzita Veterinarskeho Lekarstva, Kosice (Slovak Republic). Ustav Biologie, Zoologie a Radiobiologie | Novakova, J.,Univerzita Pavla Josefa Safarika, Kosice (Slovak Republic). Ustav Patologickej Fyziologie
The aim of the study was to observe the effect of ionizing radiation and cadmium chloride on glucose metabolism in broiler chickens. The experiment was conducted on 28-day-old chickens divided into four groups (A, B, C and D). The first group (A) served as control, groups 2 (B) and 3 (C) were irradiated with a single, whole body dose of gamma rays (3 Gy, input 1.14 Gy/min) and group 3 (C) was administered a water solution of CdCl2 intraperitoneally at a dose of 6 mg/kg body weight. Group 4 (D) was administered a water solution of CdCl2 intraperitoneally at the same dose as group 3 but chickens of this group were not irradiated with gamma rays. The serum glucose concentration in B and C chickens was decreased significantly on days 7, 14 and 21 of the experiment. The serum glucose concentration in D chickens was decreased significantly on day 7. The results of our experiment indicate that a combined influence of ionizing radiation and cadmium chloride resulted in a significant decrease in serum glucose concentration. The influence was more evident than that caused either by cadmium chloride or irradiation alone. The changes in serum glucose concentration observed on days 7 and 14 in gamma-irradiated chickens were lower than those induced by cadmium chloride.
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