Association analysis of seven candidate genes with performance traits in Czech Large White pigs
2011
Weisz, F.,Mendelova Univ., Brno (Czech Republic). Ustav Morfologie, Fyziologie a Genetiky Zvirat | Urban, T.,Mendelova Univ., Brno (Czech Republic). Ustav Morfologie, Fyziologie a Genetiky Zvirat | Chalupova, P.,Mendelova Univ., Brno (Czech Republic). Ustav Morfologie, Fyziologie a Genetiky Zvirat | Knoll, A.,Mendelova Univ., Brno (Czech Republic). Ustav Morfologie, Fyziologie a Genetiky Zvirat
Association analyses were performed between genes tagged SNP (IGF2, NAMPT, DGAT1, MYF4, MC3R, MC4R and MYOD1), performance traits (backfat thickness, lean meat content, average daily gain from birth to the end of the test, average daily gain in test) and estimated breeding values (EBVs) in a population of Czech Large White sows (n = 101). Genotyping of all SNPs was performed by SNapShot with the exception of SNP within NAMPT gene for which HpaII PCR-RFLP assay was used. The following significant associations between genes tagged SNPs and traits or EBVs were found out: DGAT1 - lean meat content (AG more than AA), MC4R - EBV for lean meat content (GG more than AA; GG more than AG), IGF2 - EBV for reproduction (piglets born alive in the second and subsequent parity) (AG more than AA) and total EBV (AG more than AA), and MC3R - EBV for average daily gain (CT more than TT).
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