Anti ageing efficacy of Phaeomeria speciosa (bunga kantan) and Piper betle (sireh)
2004
Imilia I. | Noordin M. M., Putra Malaysia Univ. (UPM), 43400 UPM Serdang, Selangor (Malaysia). Faculty of Veterinary Medicine | Mohamed S., Putra Malaysia Univ. (UPM), 43400 UPM Serdang, Selangor (Malaysia). Faculty of Food Science & Biotechnology
Lack of scientific evidence has led to the claim of two locally available herbs Phaeomeria speciosa (bunga kantan) and Piper betle (sireh) as anti-ageing agents to remain parable. Thirty, 10 month-old male Sprague Dawley rats were divided into three groups comprising of 10 rats each. Control rats were fed commercial rat pellet while the 'bunga kantan' (BK) and 'sireh' (S) groups were fed a similar diet in addition to the inclusion of 5% level of the respective herbs. Red blood cell and plasma obtained every three weeks for twelve weeks were then subjected to superoxide dismutase (SOD) and malondialdehyde (MDA) analyses. There was a tendency of an increasing trend of MDA in all groups as time advances. Nevertheless, by the 12th week, there was a significant (p less than 0.05) decrease in MDA in the BK group. Likewise, the continuing decrease (p less than 0.05) in SOD level in the control is in contrast to the ongoing elevation of this enzyme in the BK and S groups. This preliminary result showed the potential of both BK and S to act as anti-ageing agents.
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