Flavonids of garden sage (Salvia officinalis L.) and glutinous sage (Salvia glutinosa L.) | Flavonoidi obične (Salvia officinalis L.) i lepljive (Salvia glutinosa L.) žalfije
2007
Veličković, D., AD Zdravlje-Actavis Farmaceutsko-hemijska industrija, Leskovac (Serbia) | Nikolova, M., Bulgarian Academy of Sciences, Sofia (Bulgaria). Institute of Botany | Ivancheva, S., Bulgarian Academy of Sciences, Sofia (Bulgaria). Institute of Botany | Veljković, V., Tehnološki fakultet, Leskovac (Serbia)
Due to the considerable biological effects of flavonoids (preventive, antioxidative, antimicrobial) this group of compounds was analysed in garden sage (Salvia officinalis L.) and glutinous sage (Salvia glutinosa L.). The extraction of the dried plants as well as dried residue from which the essential oil was previously isolated was performed with acetone. The TLC and HPLC techniques were used for identification of flavonoids in extracts. Results show that both plant species contain flavonoids. Apigenin and its derivatives (e.g. apigenin 4'-methyl ether), scutellarein-6-methyl ether, isoscutellarein-8-methyl ether, luteolin and 6-OH-luteolin-6-methyl ether are distinctive for the species S. officinalis. Apigenin, luteolin, 6-OH-luteolin-6-methyl ether, kaempherol-3-methyl ether, quercetin-3,7,3'-trimethyl ether and quercetin-3,7,3',4'-tetramethyl ether are distinctive for the species S. glutinosa. It is interesting that the flavonoids were also detected in considerable quantities in the material from which the essential oil was isolated before. It turned out that this material which is an industrial waste may be further used and treated with the solvents of different polarity in order to isolate the flavonoids.
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