Hematological study of dogs with experimentally-induced Staphylococcus aureus infection | Хематологично изследване на кучета с експериментално-индуцирана Staphylococcus aureus инфекция
2012
Zapryanova, D., Thracian University, Stara Zagora (Bulgaria) | Chaprazov,, Thracian University, Stara Zagora (Bulgaria) | Hristov, Ts., Thracian University, Stara Zagora (Bulgaria) | Lazarov, L., Thracian University, Stara Zagora (Bulgaria) | Georgieva, T., Thracian University, Stara Zagora (Bulgaria)
The aim of our study was to analyzed changes in haematological parameters in dogs with experimentally-induced Staphylococcus aureus infection. The study was induced in 9 mongrel male dogs (experimental group) and 6 mongrel male dogs (control group) at the age of 2 years and body weight 12-15 kg. They were exposed to a 12h light-dark cycle at room temperature (20-220С). Staphylococcus infection was caused by subcutaneous application of 5 mL bacterial suspension (109 cfu/mL) of Staphylococcus aureus in the lumbal region of experimental dogs. Significant differences between the control and the experimental group could be detected during the entire study (a period of 21 days) for all haematological parameters. Dogs developed neutrophilic leukocytosis (neutrophilia), eosinopenia, monocytopenia and lymphopenia. Two days after inoculation consistent downward trend showed Hb, RBC, Platelets, Ly and Mo. Slightly decreased were Hct, MCV, Eo. Consistent upward trend showed WBC, ESR, St and Mm. Weakly elevated were Sg and MCHC. The mean platelet count and the mean Ht enhanced in the first day, but then started to decline.
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