Modulatory effects of Ginkgo biloba extract on duodenum _mucosal immunity of broilers | 银杏叶提取物对肉仔鸡十二指肠黏膜免疫的调节作用

中国人. 研究银杏叶提取物（EGB）对肉仔鸡十二指肠黏膜的免疫调节作用。将360只1日龄健康AA肉用母雏鸡随机分成5组，每组6个重复，其中1组为对照组，饲喂基础日粮；其余4组分别饲喂添加质量分数0.009%金霉素及0.15%，0.20%和0.25%EGB的日粮，试验期为42 d。分别于21和42 d取样，测定各组肉仔鸡十二指肠黏膜免疫球蛋白含量、黏膜免疫相关细胞数量和白细胞介素-2（IL-2）含量。日粮中添加质量分数0.20%，0.25% EGB可显著提高42日龄肉仔鸡十二指肠黏膜IgA、IgG、IgM含量（P0.05），提高十二指肠上皮内淋巴细胞、肥大细胞、杯状细胞数量和IL-2含量（P0.05），并且作用效果优于金霉素组（P0.05）。日粮中添加质量分数0.20%或0.25% EGB，可增强肉仔鸡十二指肠黏膜免疫功能。

英语. An experiment was conducted to investigate the modulatory effects of Ginkgo biloba extract (EGB) on duodenum mucosal immunity of broilers. Three hundred and sixty one-day-old healthy Arbor Acres female broilers were divided into five groups, each with six replicates. The first group was the control group and fed a basal diet, while the other four groups were fed the same basal diet supplemented with 0.009% aureomycin or 0.15%, 0.20%, 0.25% EGB. The experiment lasted 42 days. The contents of immunoglobulin, the numbers of mucosal immunity-associated cells and the level of interleukin-2 (IL-2) in duodenum mucosa were determined. Adding 0.20% EGB or 0.25% EGB to diet significantly increased the contents of IgA, IgG and IgM in duodenum mucosa of 42-day-old broilers (P0.05) compared with the control and the aureomycin. The numbers of intraepithelial lymphocytes, mast cells and goblet cells and the level of IL-2 in duodenum mucosa were also significantly elevated in 42-day-old broilers fed diets supplemented with 0.20% EGB or 0.25% EGB (P0.05). Adding 0.20% EGB or 0.25% EGB to diets of broilers could enhance duodenum mucosal immunity of broilers.