Results of the second field trial of a recombinant vaccine against coenurosis in sheep (Sardinia, Italy)
2011
Masala, M., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale | Pipia, A.P., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale | Tosciri, G., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale | Sanna, G., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale | Vural, G., Veterinary Control and Research Institute, Pendik, Istanbul (Turkey) | Lightowlers, M., University of Melbourne (Australia). Veterinary Centre | Varcasia, A., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale | Garippa, G., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale | Scala, A., Università degli Studi di Sassari (Italy). Dipartimento di Biologia Animale
Taenia multiceps (Leske, 1780) are a taenid cestode that in its adult stage lives in the small intestine of dogs and other canidae (Edwards et al., 1982). The larval stage of T. multiceps causes coenurosis, a frequent parasitic disease that affects the central nervous system (CNS) of various livestock species worldwide, especially sheep and other ungulates, inducing the so called cerebral cenurosis (CC). Control of coenurosis in livestock relies on the same measures as those used to prvent metacestodosis such as hydatidosis. New control measures are becoming available for coenurosis and hydatidosis to assist the more traditionalmeasures of control of slaughtering, antiparasiting treatment and control of the definitive hosts, and health education. A highly effective vaccine has been developed which can reduce hydatid infection in livestock animals (Lightowlers et al., 1996). Widespread use of this vaccine could reduce the transmission of hydatid infection to humans. A field trial for recombinant proteins against coenurosis was carried out in 2007 in five sheep farms of Sardinia, Western Mediterranean, where this metacestodosis is quite common in sheep flocks. The recombinant proteins used for vaccination, confirmed the lack of any risk for the vaccinated animals, which showed no swelling in the area of inoculation, and nor other adverse effects. The field trial of recombinant vaccine against Taenia multiceps used would appear to be already at this early stage, given the high degree of effectiveness monitored, a garrison eligible for any routine application in field situations at particular risk of infection.
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