Enterocin 4231 produced by Enterococcus faecium CCM 4231 and its use in rabbits
2011
Szabóová, R., Slovak Academy of Sciences, Košice (Slovak Republic). Institute of Animal Physiology | Lauková, A., Slovak Academy of Sciences, Košice (Slovak Republic). Institute of Animal Physiology | Chrastinová, L., Centre of Animal Nutrition Research, Nitra Lužianky (Slovak Republic) | Pogány-Simonová, M., Slovak Academy of Sciences, Košice (Slovak Republic). Institute of Animal Physiology | Strompfová, V., Slovak Academy of Sciences, Košice (Slovak Republic). Institute of Animal Physiology | Plachá, I., Slovak Academy of Sciences, Košice (Slovak Republic). Institute of Animal Physiology | Čobanová, K., Slovak Academy of Sciences, Košice (Slovak Republic). Institute of Animal Physiology | Vasilková, Z., Slovak Academy of Sciences, Košice (Slovak Republic). Parasitological Institute | Chrenková, M., Centre of Animal Nutrition Research, Nitra Lužianky (Slovak Republic)
The aim of this experiment was to study the effect of Enterocin (Ent) 4231 produced by Enterococcus faecium. The group of 48 rabbits (Hy-Plus breed) was divided into experimental (EG) and control (CG) group. In EG Ent 4231 was applied for 21 days in a dose of 50 microL/animal/day into drinking water. The experiment lasted for 42 days. Samples were collected on day 0-1, day 7, day 21 (3 weeks of administration) and on day 42 (3 weeks after cessation of application) to measure the occurence of Eimeria sp. oocysts. Samples of caecal contents were collected on days 21 and 42 to determine bacterial counts. The phagocytic activity was examined on days 0-1, 21 and 42. On days 21 and 42 the reduction of Clostridium-like sp. was detected in EG (difference 1.53 log sub(10) CFU/g; 1.57 log sub(10) CFU/g) in comparison with CG. In EG on day 7 the decrease of E. coli (difference 1.30 log sub(10) CFU/g) was also noted in comparison with CG. In EG prolonged immunostimulative effect (p is less than 0.001) was observed on day 42 in comparison with CG. The oocysts of Eimeria sp. were reduced in EG comparing with CG at day 42. Enrichment of the diet for rabbits with Ent 4231 did not influence biochemical, zootechnical parameters and the values of caecal content volatile acids during the whole experiment.
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