Effect of exposure to sublethal concentrations of zinc cyanide on tissue ATPase activity in the fresh water fish, Cirrhinus mrigala (Ham)
2012
Dube, S.A., School of Biological Sciences, Shimoga, Karnataka (India). Department of Applied Zoology | Hosetti, B.B., School of Biological Sciences, Shimoga, Karnataka (India). Department of Applied Zoology
The present study was conducted to evaluate the effects of zinc cyanide (Zn(CN)2) on the ATPase (Na+-K+-, Mg2+, Ca2+) activity of the freshwater fish Cirrhinus mrigala (Ham). Fish were exposed to two sublethal concentrations (0.114 and 0.068 mg/L) and the effects were studied in the liver, muscle and gill tissues at the end of 5, 10 and 15 days of exposure. Cyanide intoxication resulted in marked changes in ATPases, represented by a significant decrease in the activities. Maximum inhibition was observed at higher concentration. The order of inhibition in the activity was Na+-K+- greater than Ca2+ greater than Mg2+ ATPase. These results imply an immediate adaptive response to the stress, demonstrating alterations in ATPase activities in the tissues of cyanide-treated fish. The present study clearly proposes that ATPases can be used as biomarkers of exposure of aquatic organisms to cyanide intoxication.
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