Characteristics of laboratory findings in dogs with liver disease - testing of clinical significance | Karakteristike laboratorijskog nalaza kod pasa sa bolestima jetre - ispitivanje kliničkog značaja
2012
Belić, B., Poljoprivredni fakultet, Novi Sad (Serbia) | Cincović, M.R., Poljoprivredni fakultet, Novi Sad (Serbia) | Neckov, S., Poljoprivredni fakultet, Novi Sad (Serbia)
The aim of this study was to investigate the clinical significance of laboratory findings in dogs with liver disease. The metabolic profile in dogs with liver disease showed a significantly higher concentration of ALT, AST, AP, GGT and bilirubine, while the concentration of urea and cholesterol were significantly lower. There was a significant link between elevated levels of ALT, AST, AP, GGT and bilirubine with the existence of liver disease dogs. AP and AST have the greatest clinical significance, while ALT, GGT and bilirubine have somewhat lower values of sensitivity and specificity. By determining the most important factors that indicate liver health are two factors stand out. For the purpose of extracting the most important factors that influence the metabolic profile and blood count was found a significant effect of two factors. The first factor explained 79.7% of variation of all parameters and maximum values correlated with ALT and AP, and the second factor accounts for 14.4% of the variability of all parameters and maximum was correlated with bilirubine. The results highlight the clinical significance of ALT, AP and bilirubine.
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