Metabolic responses in endurance horses during racing in relation to uric acid profile, leucocytes, heart rate and plasma biochemical parameters
2012
Adamu, L., University Putra Malaysia, Serdang (Malaysia). Faculty of Veterinary Medicine | Noraniza, M.A., University Putra Malaysia, Serdang (Malaysia). Faculty of Veterinary Medicine | Rasedee, A., University Putra Malaysia, Serdang (Malaysia). Faculty of Veterinary Medicine | Bashir, A., University Putra Malaysia, Serdang (Malaysia). Faculty of Veterinary Medicine
The aim of our study was to investigate the changes in uric acid, leukocytes, plasma biochemical parameters and heart rate in metabolic endurance horses. Thirty Arabian endurance horses were physically examined and blood samples were collected pre and post-race. After physical examination, the successfully completed (n = 10) and metabolic disordered (n = 20) endurance horses were identified. Blood samples in heparinised vacutainer tubes were used for the determination of uric acid, triglycerides, creatine kinase, aspartate transaminase, packed cell volume, lactate, total protein and plasma protein. Blood samples in ethyl diaminotetra-acetic acid vacutainer tubes were used for the analysis of leukocytes. The age, body weight, heart rate, humidity and ambient temperature were also recorded. One way analysis of variance and pairwise correlations were used for the analysis. The mean values of uric acid, lactate, leukocytes, packed cell volume, plasma protein, total protein, heart rate, creatine kinase, aspartate transaminase and triglycerides were significantly different between the successful and matabolic disordered endurance horses. There were significant positive correlations between uric acid and lactate (r = 0.5196; P less than 0.0271), between uric acid and plasma protein (r = 0.6025; P less than 0.0175), between uric acid and packed cell volume (r = 0.5206; P less than 0.0268), between uric acid and triglycerides (r = 0.5541; P less than 0.0170) and between uric acid and heart rate (r = 0.5629; P less than 0.0150) in the metabolic disordered endurance horses. In conclusion, heart rate, triglycerides, blood lactate and packed cell volume were significantly associated with uric acid, a biomarker of oxidative stress. Therefore, uric acid could be used to evaluate performance and health status in endurance horses during training and endurance events.
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