Association of Microsatellite Marker in FABP4,5 Gene with Marbling Score and Feeding and Management in Breed Hanwoo
2012
Kim, B.S., Agricultural Technology Center of Ansung City, Ansung, Republic of Korea | Chang, K.W., National Institute of Animal Science, RDA, Suwon, Republic of Korea | Lee, S.H., National Institute of Animal Science, RDA, Suwon, Republic of Korea | Chung, H.J., National Institute of Animal Science, RDA, Suwon, Republic of Korea | Yang, B.S., National Institute of Animal Science, RDA, Suwon, Republic of Korea | Park, J.K., National Institute of Animal Science, RDA, Suwon, Republic of Korea | Kim, M.S., Hankyong National University, Ansung, Republic of Korea | Lim, S.H., Hankyong National University, Ansung, Republic of Korea | Park, C.W., Hankyong National University, Ansung, Republic of Korea | Min, K.S., Hankyong National University, Ansung, Republic of Korea | Yang, B.C., National Institute of Animal Science, RDA, Suwon, Republic of Korea
The bovine fatty acid binding protein 4 and 5 (FABP4 and 5) is a major positional and physiological candidate gene for the bovine marbling and carcass weight. The aim of this study was to evaluate the association between economic traits of Korean cattle (Hanwoo) and genetic variation in fatty acid binding protein 4 and 5 (FABP4 and 5) genes within carcass/meat quality traits and the before/after of fatting in breed Hanwoo. Here, we characterized the nucleotide polymorphism of FABP4 and 5 in 86 cattle. We were detected the variability of three types (GG, AG, and AA) by PCR, and economic traits were analyzed by the mixed regression model implemented in the ASReml program. As the result of statistical and supersonic analysis, FABP4 gene was highly showed significant effect (p less than 0.006) on marbling score (MS), in contrast FABP5 gene was lowed (p less than 0.084) on MS before fatting. But, FABP4 gene was highly showed significant effect (p less than 0.0054) on MS, in contrast FABP5 gene lowest (p less than 0.0899) on MS in the after of fatting. Compare to supersonic result before fatting in FABP4 gene, it was detected type GG: (p less than 7.18), AG: (p less than 8.50), and AA: (p less than 10.50) (n=50), showed type GG: (p less than 4.88), AG: (p less than 2.33), and AA: (p less than 0.00) after weed out (n=20). Futhermore, it was detected type GG: (p less than 9.30), AG: (p less than 7.95), and AA: (p less than 7.40) (n=50) before fatting in the FABP5 gene. It was shown type GG: (p less than 2.67), AG: (p less than 3.50), and AA: (p less than 5.00) after weed out (n=50). Our results indicate that FABP4 and 5 gene transcription is regulated by the environment of feeding and management, and suggest that feeding and management could be potential key in determining FABP4 and 5 genes transcription for carcass/meat quality traits in breed Hanwoo.
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