Evaluation of the difference of L-selectin, tumor necrosis factor-alpha and sialic acid concentration in dairy cows with subclinical ketosis and without subclinical ketosis
2013
Zhang, Z.G. (Northeast Agricultural Univ., Harbin (China). Coll. of Veterinary Medicine) | Xues, J.D. (Inner Mongolia Univ. for Nationalities, Tongliao (China). Coll. of Animal Science and Technology) | Gao, R.F. (Jilin Univ., Changchun (China). Coll. of Animal Science and Veterinary Medicine) | Liu, J.Y. | Wang, J.G. | Yao, C.Y. | Liu, Y. | Li, X.W. | Li, X.B. | Liu, G.W. | Wang, Z.
Ketosis is a major disease related with negative energy balance and immune suppression in dairy cows. The objective of this study was to examine the differences in beta-hydroxybutyrate (BHBA), L-select in glucose, tumor necrosis factor-alpha (TNF-alpha), non-esterified fatty acids (NEFA), and sialic acid (SA) concentrations in serum in healthy dairy cows and those with sub-clinical ketosis during the early lactation period. The blood from 20 healthy cows and 20 sub-clinically affected cows were sampled. All the cows were within the first 2 months of lactation. Serum concentrations of the various aforementioned factors were measured using a number of different methods. The results demonstrated that in cows affected by sub-clinical ketosis, NEFA concentrations were significantly higher, and glucose and L-selectin concentrations were significantly lower than healthy cows. There was no significant difference in serum SA and TNF-alpha of dairy cows with sub-clinical ketosis compared to the control cows. The decrease in concentration of serum L-selectin may be related to immune suppression.
显示更多 [+] 显示较少 [-]