Metastatic thyroid C-cell carcinoma in a beagle dog
2013
Lee, S., Irion Animal Hospital, Seoul, Republic of Korea | Lee, M., Irion Animal Hospital, Seoul, Republic of Korea | Youp, K., Irion Animal Hospital, Seoul, Republic of Korea | Lee, A., Irion Animal Hospital, Seoul, Republic of Korea | Won, S., Irion Animal Hospital, Seoul, Republic of Korea | Kim, M., Seoul National University, Seoul, Republic of Korea | Kim, S., Seoul National University, Seoul, Republic of Korea | Kim, Y., Seoul National University, Seoul, Republic of Korea
An adult beagle dog was presented with a cervical mass detected by palpation and computed tomography. Fine needle aspirates revealed numerous epithelial cells with plasmacytoid appearance and frequent naked nuclei. Histologically, the mass consists of multiple packets of neoplastic cells and extensive areas of necrosis and fibrosis. Neoplastic cells were also found in submandibular lymph nodes. Immunohistochemistry showed that neoplastic cells were positive for calcitonin and negative for thyroglobulin. Based on these findings, the cervical mass was diagnosed as thyroid C-cell carcinoma. Almost one year after the surgical excision, the dog remains healthy without any symptom of recurrence or metastasis.
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