Effect of Diets with Job's Tears and Cudrania tricuspidata Leaf Mixed-powder Supplements on Body Fat and Serum Lipid Levels in Rats Fed a High-Fat Diet
2012
Park, J.H., Korea Food Research Institute, Seongnam, Republic of Korea | Lee, K.W., Korea Food Research Institute, Seongnam, Republic of Korea | Sung, K.S., Korea Food Research Institute, Seongnam, Republic of Korea | Kim, S.S., Korea Food Research Institute, Seongnam, Republic of Korea | Cho, K.D., Food One Tech Inc., Seoul, Republic of Korea | Lee, B.H., Chung-Ang University, Anseong, Republic of Korea | Han, C.K., Korea Food Research Institute, Seongnam, Republic of Korea
This study investigated the effects of diets with a supplement of Job's tears (JT) and Cudrania tricuspidata leaf (CTL) powder as a functional food ingredient on obesity and lipid profiles in diet-induced obese rats. Male Sprague-Dawley rats were fed a high-fat diet (D12492, 45 kcal fat) for 5 weeks during the first phase. In the second phase, which lasted 5 weeks, the rats were divided into four experimental groups. The groups were a high-fat diet group as a control (HFD), a high-fat diet with 10% JT powder supplement group (JT-10), a 10% CTL powder supplement group (CTL-10), and a 20% JT and CTL 1:1 mixed-powder supplement group (MIX-20). The adipose tissue (RFP, EFP) weights were significantly decreased in the CTL-10 and MIX-20 groups than in the HFD group (p less than 0.05). The fecal weight produced by the MIX-20 group was highest among all experimental groups (p less than 0.05), and it was significantly increased during the second phase compared to the first phase (p less than 0.05). The serum total cholesterol content was significantly decreased in the CTL-10 and MIX-20 groups, and the LDL-cholesterol content was significantly low in the JT-10 and MIX-20 groups than in the HFD group (p less than 0.05). The blood glucose levels were significantly decreased in all experimental diet supplement groups than in the HFD group (p less than 0.05). The findings show that a diet of mixed JT and CTL could improve lipid metabolism.
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