Smoking Habits and Neuropeptides : Adiponectin, Brain-derived Neurotrophic Factor, and Leptin Levels
2014
Kim, K.W., Korea Occupational Safety and Health Agency, Incheon, Republic of Korea | Won, Y.L., Korea Occupational Safety and Health Agency, Incheon, Republic of Korea | Ko, K.S., Korea Occupational Safety and Health Agency, Incheon, Republic of Korea | Roh, J.W., Korea Occupational Safety and Health Agency, Incheon, Republic of Korea
This study aimed to identify changes in the level of neuropeptides among current smokers, former smokers, and individuals who had never smoked, and how smoking habits affect obesity and metabolic syndrome (MetS). Neuropeptide levels, anthropometric parameters, and metabolic syndrome diagnostic indices were determined among male workers; 117 of these had never smoked, whereas 58 and 198 were former and current smokers, respectively. The total sample comprised 373 male workers. The results obtained from anthropometric measurements showed that current smokers attained significantly lower body weight, body mass index, waist circumference, and abdominal fat thickness values than former smokers and those who had never smoked. Current smoker eating habits proved worse than those of non-smokers and individuals who had never smoked. The level of brain-derived neurotrophic factor (BDNF) in the neuropeptides in the case of former smokers was 23.6 ¡¾ 9.2 pg/ml, higher than that of current smokers (20.4 ¡¾ 6.1) and individuals who had never smoked (22.4 ¡¾ 5.8) (F = 6.520, p = 0.002). The level of adiponectin among former smokers was somewhat lower than that of current smokers, whereas leptin levels were higher among former smokers than current smokers; these results were not statistically significant. A relationship was found between adiponectin and triglyceride among non-smokers (odds ratio = 0.660, ¥� value = ?0.416, p 0.01) and smokers (odds ratio
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