Metabolic and haematological parameters in paretic cows that received and not received ketoprofen (Case report)
2015
Kovačević, Zorana (Faculty of Agriculture, Novi Sad (Serbia)) | Cincović, Marko R. (Faculty of Agriculture, Novi Sad (Serbia)) | Belić, Branislava (Faculty of Agriculture, Novi Sad (Serbia)) | Stojanović, Dragica (Faculty of Agriculture, Novi Sad (Serbia)) | Davidov, Ivana (Faculty of Agriculture, Novi Sad (Serbia))
In the period after calving in cows there are many endocrin and metabolic changes because of the increase in energy demand which can cause numerous diseases including puerperal paresis, which is caused by hypocalcemia. The aim of this study was to compare the metabolic and hematological parameters in the first and second week after calving in paretic cows which is administered ketoprofen during three days after calving. Blood samples were taken from cows with postpartum paresis 7 and 14 days after calving. We examined the blood count (number of leukocytes, neutrophils, lymphocytes, red blood cells and hemoglobin concentration) and metabolic profile of cows (total protein, albumin, bilirubin, Ca, P, glucose, hoelsterol, AST, GGT, NEFA, BHB). Application ketoprofen does not lead to significant differences in the absolute values of the parameters. However, there was a significant difference in the dynamic changes in the blood picture and metabolism in the second week after birth compared to the first, so that cows that received ketoprofen have less lipid mobilization and ketogenesis, less load hepatocytes and favorable ratio of neutrophils and lymphocytes. We conclude that the use of ketoprofen may be useful as a form of supportive therapy, as it reduces the intensity of lipid mobilization and ketogenezis, and relieves the symptoms of inflammatory response and liver dysfunction in paretic cows.
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