Coxiella burnetii phase-specific serological response and status of offspring in dairy cows in Latvia – preliminary results | Coxiella burnetii antigēna fāzes specifiskā imūnatbilde un pēcnācēja statuss slaucamām govīm Latvijā – sākotnējie rezultāti
2018
Ringa-Karahona, G., Latvia Univ. of Life Sciences and Technologies, Jelgava (Latvia). Faculty of Veterinary Medicine | Antane, V., Latvia Univ. of Life Sciences and Technologies, Jelgava (Latvia). Faculty of Veterinary Medicine | Grantina-Ievina, L., Institute of Food Safety, Animal Health and Environment „BIOR”, Riga (Latvia)
Coxiella burnetii – an etiological agent of zoonosis Q fever – can be present in two phases of antigen: phase1 (Ph1) and phase2 (Ph2). Phase-specific serological response demonstrates chronic (Ph1) or acute (Ph2) C. burnetii infection. Outcomes of C. burnetii infection in cows can be late-term abortion, stillbirth, weak or normal offspring. The aim of this study was to detect C. burnetii phase-specific serological response and status of offspring in dairy cows. This is the first study to detect this relation in dairy cows in Latvia. In 2017, sera samples from 44 randomly selected animals belonging to 5 herds with previous history of C. burnetii infection were collected from different parishes in Latvia for this study. Samples were tested by “VetLine Coxiella Phase1 and Phase2 ELISA” (NOVATEC). Data of status of the last parturition/offspring were collected from Agricultural Data Centre of Republic of Latvia. Status of offspring was defined as abortion, stillbirth, died and alive. Statistical processing of data was performed using Pearson’s Chi-squared test (RStudio). There were 6 cows with a positive serological response to Ph1 (Ph1+), 3 cows with a questionable serological response to Ph1 (Ph1+/-) and 35 cows without any serological response to C. burnetii. Outcome of offspring alive was significantly (p is less than 0.05) lower in Ph1+ cows compared to Ph1+/- and those without any serological response to C. burnetii. The possible inaccuracies in the interpretation of this study’s results could be due to non-performed PCR of C. burnetii presence in offspring. We will focus on that aspect in future, and the study will be continued.
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