Antibiofilm activity of the essential oil of citronella (Cymbopogon nardus) and its major component, geraniol, on the bacterial biofilms of Staphylococcus aureus
2019
Pontes, E.K.U., University Center UNINTA, Sobral, Brazil | Melo, H.M., University Center UNINTA, Sobral, Brazil | Nogueira, J.W.A., University Center UNINTA, Sobral, Brazil | Firmino, N.C.S., University Center UNINTA, Sobral, Brazil | de Carvalho, M.G., Federal Rural University of Rio de Janeiro, Serope´dica, Brazil | Catunda Junior, F.E.A., State University of the Tocantina Region of Maranhao, Imperatriz, Brazil | Cavalcante, T.T.A., University Center UNINTA, Sobral, Brazil
Medicinal plants with antimicrobial action have been investigated for uses against biofilms, among which, Cymbopogon nardus, citronella, stands out as a promising species. The present study aims to evaluate the antimicrobial and antibiofilm action of the essential oil of C. nardus (EOCN) and geraniol on Gram-negative and positive bacteria from the determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration and inhibition of biofilms. In the results, the EOCN produced a 41 mm halo on S. aureus, which was susceptible with MIC values of 0.5 and 0.25 mg/mL for the EOCN and geraniol respectively, both with bactericidal effect. The antibiofilm action was confirmed, the EOCN and geraniol reduced the biofilm biomass of S. aureus up to 100% between 0.5 and 4 mg/mL concentrations. The reduction of cell viability was 0.25 and 1 mg/mL, of EOCN and geraniol, respectively. EOCN and geraniol were shown to be promising antibiotic against S. aureus.
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