How yeast cell wall components can alleviate mycotoxicosis in animal production and improve the safety of edible animal products
2005
Jouany, J.P. | Yiannikouris, A. | Bertin, Gaelle
Several authors have reported that the addition of yeast cell walls to contaminated feeds alleviates the harmful effects of mycotoxins, but nothing is known on the chemical interactions between the binder and the toxins. We showed that beta-D-glucans are the yeast component responsible for the complexation of mycotoxins, and that the reticular organization of beta-D-glucans and the distribution between beta-(1,3)-D-glucans and beta-(1,6)-D-glucans play a major role in the efficacy. Weak hydrogen and van der Waals bonds are involved in the complexation of mycotoxins by beta-D-glucans, thus indicating that the chemical interaction is more of "adsorption type" than "binding type". We performed molecular modelling and calculated potential energy to estimate the stability of the complexes.
显示更多 [+] 显示较少 [-]