Cytotoxicity, antioxidant and antimutagenic potential evaluation of peels of edible roots and tubers
2019
Sarwari, G. | Sultana, B. | Sarfraz, R. A. | Zia, M. A.
The peels of edible roots and tubers contain nutritionally and industrially important compounds but are frequently discarded as agro-waste. In the present work, the peels of radish (Raphanus sativus), turnip (Brassica rapa), beetroot (Beta vulgaris), sweet potato (Ipomoea batatas), and potato (Solanum tuberosum) were analysed for their potential cytotoxicity in terms of haemolytic activity; antioxidant activity in terms of total phenolic contents (TPC); DPPH radical scavenging assay, and antimutagenic activity using Ames bacterial reverse mutation test. Characterisation of individual phenolic acids was performed using high-performance liquid chromatography (HPLC). The haemolytic activity of radish, turnip, potato, sweet potato, and beetroot peels ranged from 0.34 - 4.85% and the TPC ranged from 43.82 - 67.23 mg GAE/g DW. Strong antimutagenic behaviour was exhibited by beetroot peels while sweet potato peels were found to be weak antimutagenic agent. Overall, the result infers that peels of selected edible roots and tubers are a rich source of antioxidants with good antimutagenic potential but weak cytotoxicity towards normal human blood cells. Therefore, the peels of roots and tubers can be used as feed, food and natural pharmaceutical or chemo-preventive agent after applying suitable processing techniques rather than discarded as agro-waste.
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