Collagen extraction process
2016
Mello, R. O. | Dornelles, R. C. P. | Mazutti, M. | Kempka, A. P. | Schmidt, M. M. | Demiate, I. M. | Kubota, E. H.
Collagen is a fibrous protein which is dominant in the connective tissue of animals; it has a wide range of applications in the food, pharmaceutical, cosmetic and photographic industries, among others. There is a growing interest in the extraction process of collagen and its derivatives due to the growing tendency to use this protein to replace synthetic agents in various industrial processes, which results in a greater appreciation of the by-products from animal slaughter. Collagen’s characteristics depend on the raw material and the extraction conditions, which subsequently determine its application. The most commonly used extraction methods are based on the solubility of collagen in neutral saline solutions, acid solutions, and acid solutions with added enzymes. Recently, the use of ultrasound, combined with these traditional processes, has proven effective in increasing the extraction yield. The objective of this review is to address the different collagen extraction processes, from raw materials to the use of combinations of chemical and enzymatic processes, as well as the use of ultrasound. The information outlined in this article have been collected from different national and international journals in Agricultural Sciences e Science and Food Technology, using four bibliographic databases and also some books of renowned authors. Were selected articles published between 2000 and 2015, to address the different collagen extraction processes have been studied.
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