Gender differences on the effects of honey and black seed mixture supplementation
2017
Hayati Mohd Yusof | Mohamad Azlan Manan | Norizah Mhd Sarbon | Asma’ Ali
The effects of black seed and honey on cardiovascular disease (CVD) risk factors have been widely studied. However, few studies were done on its mixture especially on gender differences. Hence, this prospective open labelled supplementation study was aimed to investigate the effect of black seed and honey mixture (1:1 ratio) on CVD risk factors including lipid profile, blood pressure, blood glucose and hemoglobin, based on gender differences. Forty-one subjects recruited among Universiti Malaysia Terengganu staffs participated in this study, males (n=17) and females (n=23). Bothgroups were supplemented with black seed and honey mixture (2.3 g/day) for forty-five days (1.5 month). Venous bloods were taken before and after the study for analysis of lipid profile, hemoglobin and glucose concentrations. The supplementation shows a significanteffect among gender. Females exhibit favorable effects on hemoglobin (p=0.007), systolic blood pressure (p=0.002), blood glucose (p=0.003) and total cholesterol (p=0.039). On the other hand, males show favorable effects on blood glucose (p=0.008) and total cholesterol (p=0.030). However, in terms of lipid profile, males tend to get more benefit following supplementation as compared to their female counterparts. Future investigations with larger sample size, longer duration period with several time points, dosage differences and effect of supplementation towards liver function and inflammatory markers are suggested to verify the present findings.
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