Anticoccidial effects of Tinospora rumphii extract in naturally infected goats
2022
Pearl Muyco Saladino (College of Veterinary Medicine, University of Southern Mindanao, Kabacan, Cotabato, Philippines) | Elsa Amarille Gonzaga (Department of Veterinary Paraclinical Sciences, College of Veterinary Medicine, University of Southern Mindanao, Kabacan, Cotabato, Philippines) | Loveille Jun Amarille Gonzaga (Department of Chemistry, College of Science and Mathematics, University of Southern Mindanao, Kabacan, Cotabato, Philippines.)
Objective: This study aimed to determine the anticoccidial potential of Tinospora rumphii ethan¬olic stem extract, resulting in an effective reduction in oocysts per gram counts of Eimeria species in goats in comparison to the commercial coccidiostat toltrazuril. Materials and Methods: Eighteen goats that were naturally infected with coccidia were identified as experimental animals. The experimental animals were grouped and were administered a single dose of T. rumphii extract at concentrations of 300, 600, 1,000, and 2,000 mg extract/kg body weight. The fecal samples were collected before treatment, during the first treatment, and every week thereafter for 28 days posttreatment. Fecal examination was carried out using a modified McMaster technique to determine the oocysts per gram of feces, and the mean efficacies of the extracts were calculated. Results: Stem extracts of T. rumphii were able to lower the oocysts per gram count than pre¬treatment for all concentrations, but the efficacy, in general, was still lower than toltrazuril. A significant difference existed in the efficacy of the extracts among the treatments on day 14. Administering 1,000 mg/kg extract resulted in the highest efficacy rate (95.25%) at 14 days post¬treatment and was comparable to that of toltrazuril (89.89%). Conclusion: The results show that the T. rumphii stem extract has the potential to reduce the Eimeria species oocysts per gram counts of naturally infected goats. [J Adv Vet Anim Res 2022; 9(1.000): 8-12]
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