The Interplay between Adeno-Associated Virus and its Helper Viruses
2020
Anita F. Meier | Cornel Fraefel | Michael Seyffert
The adeno-associated virus (AAV) is a small, nonpathogenic parvovirus, which depends on helper factors to replicate. Those helper factors can be provided by coinfecting helper viruses such as adenoviruses, herpesviruses, or papillomaviruses. We review the basic biology of AAV and its most-studied helper viruses, adenovirus type 5 (AdV5) and herpes simplex virus type 1 (HSV-1). We further outline the direct and indirect interactions of AAV with those and additional helper viruses.
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书目信息
出版者
MDPI AG
其它主题
Viral coinfections; Adenovirus; Helper virus; Viral vectors
语言
英语
类型
Journal Article
来源
Viruses, Vol 12, Iss 662, p 662 (2020)
2022-09-15
AGRIS AP