The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G<sub>2</sub>Arrest in Cryptococcus

Sophie Altamirano; Zhongming Li; Man Shun Fu; Minna Ding; Sophie R. Fulton; J. Marina Yoder; Vy Tran; Kirsten Nielsen

The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G<sub>2</sub>Arrest in Cryptococcus

2021

Dysregulation of the cell cycle underlies many human genetic diseases and cancers, yet numerous organisms, including microbes, also manipulate the cell cycle to generate both morphologic and genetic diversity as a natural mechanism to enhance their chances for survival. The eukaryotic pathogenCryptococcus neoformans

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