The isolation and nucleotide sequence of the pyruvate decarboxylase gene from Kluyveromyces marxianus

Holloway, P. . Dept. of Microbiology; Subden, R.E.

The isolation and nucleotide sequence of the pyruvate decarboxylase gene from Kluyveromyces marxianus

1993

Holloway, P. (Guelph Univ., Ontario (Canada). Dept. of Microbiology) | Subden, R.E.

The nucleotide sequence of a 2360-basepair (bp) region of the Kluyveromyces marxianus genome containing the structural gene for the enzyme pyruvate decarboxylase (PDC) was determined. Comparison of the deduced amino-acid sequence of this gene to that of the Saccharomyces cerevisiae PDC genes reveals extensive homology including a motif common to thiamin diphosphate-dependent enzymes.

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