Effect of emissions from a mercury treating metallurgical works on the intensity of experimental Fasciola hepatica infection in sheep
1996
Krupicer, I. | Velebny, S. (Slovenska Akademia Vied, Kosice (Slovakia). Parazitologicky Ustav) | Legath, J.
A group of 14 improved Valashka lambs, aged 4 months, body weight 14-16 kg, were used in the experiment studying the effect of subchronic heavy metal intoxication on the course of experimental fasciolosis (Fasciola hepatica). Each animal in group I was given orally for 27 days gelatinous capsules containing heavy metal emissions of the following composition: 4.5 mg Hg, 2.9 mg Pb, 147.8 mg Cu, 9.8 mg Zn, 0.9 mg Cr per animal and dry. Group II served as control. On day 27, each animal in both groups received 250 F. hepatica metacercariae. In subchronically intoxicated animals, the reference values for mercury were exceeded and so were partially those of copper in the parenchymatous organs and muscles. The F. hepatica infection mean intensity also increased, compared with control. The results have proved the negative effect of the metal emissions on the animal immune system, which was manifested by the increased infection intensity.
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