Ultrasound spirometry in the horse: a preliminary report on the method and the effects of xylazin and lobelin hydrochloride medication
1997
Herholz, C. | Tschudi, P. | Gerber, H. | Moens, Y. | Straub, R. (Bern Univ. (Switzerland). Division of equine internal medicine, Clinic for horses and farm animals)
A new computerised ultrasound-based spirometry system according to Buess et al. (1995), modified by a double-flow measurement facility was used to study the pulmonary function in healthy horses and horses affected with subclinical and manifest chronic bronchiolitis (CB). The horses were first evaluated at rest without any medication. On anonther occasion all horses were tested following i.v. administration of xylazine (0.4 mg/kg) and following i.v. administration of lobelin hydrochloride (l.hy.; 0.2 mg/kg) to evaluate the effect of xylazine and l.hy. on different spirometric variables. Ultrasound-based spirometry proved to be an easily applicable method for lung function testing, even in difficult horses. However, there existed a pronounced physiological variation for all measured lung function parameters and no significant differences between healthy horses and horses with chronic bronchiolitis could be found except for the expiratory tidal volume (VTE, p 0.05). Individually, a marked decrease of variability from breath to breath following either xylazin and l.hy. administration could be observed for all parameters, except the flow-time-ratio (Tpef./Texp.) and the flow-volume-ratio (Vpef./Vexp.)
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