An attempt to improve the solubility and stability of Ocimum tenuiflorum aqueous leaves extract
2021
Muhammad Ezzudin, R. | Rohini, J. | Rabeta, M. S.
Medicinal plants have gained attention in recent years due to the presence of various bioactive compounds which promote distinct health benefits and is less toxic. However, the plants face common and serious problems due to their active compounds which are the solubility and stability. Ocimum tenuiflorum, one of the ancient medicinal plants were its medicinal values have been widely studies. Yet, study to improve its quality still lacking. Thus, an effort was taken to study and improve the solubility and stability of the plant. Solid dispersions were prepared with extract and different types of surfactants at different ratio have used to improve the stability. Lecithin (1:1 ratio) have improved the solubility significantly (p<0.05) when compared to extract. Enhancement in solubility, hence improved the stability when stored at 4°C of the solid dispersion of extract. Overall, the study has successfully improved the quality of the extract with lecithin complex whereby the solubility and increases stability.
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