Embryonic stem cells in cattle
2008
Munoz, M | Diez, C | Caamano, Jn | Jouneau, Alice | Hue, Isabelle | Gomez, E. | SERIDA | Biologie du développement et reproduction (BDR) ; École nationale vétérinaire - Alfort (ENVA)-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS)
International audience
显示更多 [+] 显示较少 [-]英语. Because of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals-related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated. In this paper, we will summarize the current knowledge on bovine ESCs in an attempt to understand why derivation of domestic animal ESC is still unsuccessful and we will discuss some promising future approaches.
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