The effect of oral contraceptive agents on copper and zinc balance in young women
1978
Crews, Michael Glen
Abstract: Two groups of women between 19 and 25, one on oral contraceptive therapy and a control group, living under normal conditions and eating a diet chosen from common foods with zinc and copper levels approximating normal, were studied to determine the effect of oral contraceptives on these levels. The literature search focused on the metabolic actions of copper and zinc, and on the effects of oral contraceptives on zinc, copper, steroids, lipids, and vitamins. The parameters used were urinary content, fecal content, and balance; nitrogen was also measured by these parameters. Results indicated no significant difference in balance levels for zinc, copper, or nitrogen. Blood plasma analysis indicated higher levels of copper and cholesterol for users of oral contraceptives. Results appear to indicate the RDA for zinc is adequate for women in this age group who use oral contraceptives, but the RDA for copper may be inadequate.
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