Eye, retina, and visual system of the mouse
2008
Chalupa, Leo M. | Williams, Robert W.
This comprehensive guide to current research captures the first wave of studies in the field, with fifty-nine chapters by leading scholars that demonstrate the usefulness of mouse models as a bridge between experimental and clinical research. The opening chapters introduce the mouse as a species and research model, discussing such topics as the mouse's evolutionary history and the mammalian visual system. Subsequent sections explore more specialized subjects, considering optics, psychophysics, and the visual behaviors of mice; the organization of the adult mouse eye and central visual system; the development of the mouse eye (including comparisons to human development); the development and plasticity of retinal projections and visuotopic maps; mouse models for human eye disease (including glaucoma and cataracts); and the application of advanced genomic technologies (including gene therapy and genetic knockouts) to the mouse visual system. Readers of this reference will see th.
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