SnapShot: The Germinal Center Reaction
2014
Victora, Gabriel D.
To produce high-affinity antibodies, B cells must undergo iterative cycles of targeted mutagenesis and affinity-based selection. These cycles take place in a structure known as the germinal center, which forms in secondary lymphoid organs upon exposure to antigenic stimuli. Here, we summarize our current understanding of the germinal center reaction.
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书目信息
出版者
Elsevier Inc.
其它主题
Site-directed mutagenesis
语言
英语
类型
Journal Article; Text
2024-02-27
MODS