Oxidative stress by Haemonchus contortus in lambs: Influence of treatment with zinc edetate
2015
Pivoto, Felipe Lamberti | Torbitz, Vanessa Dorneles | Aires, Adelina Rodrigues | da Rocha, José Francisco Xavier | Severo, Marcelo Machado | Grando, Thirssa Heleno | Peiter, Mateus | Moresco, Rafael Noal | da Rocha, João Batista Teixeira | Leal, Marta Lizandra do Rego
The aim of the present study was to assess the effects of zinc edetate on the oxidative stress of lambs infected by Haemonchus contortus. Twenty-four lambs were allocated into four groups: Group I — uninfected animals; Group II — uninfected animals treated subcutaneously with zinc edetate; Group III — animals infected by H. contortus and Group IV — animals infected and treated. The oxidative stress index (OSI) and the eggs per gram of feces (EPG) were assessed after 10, 17, 24, 31 and 38days post-infection. Based on the EPG and the quantity of adult H. contortus, the infection did not differ between groups III and IV. Zinc edetate reduced the OSI in Group IV in relation to Group I after 24days post-infection, and in relation to group III after 31days post-infection. Treatment with zinc edetate could help reduce the oxidative stress induced by H. contortus in lambs.
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