Properties of a Bayesian approach to detect QTL compared to the flanking markers regression method
1998
Scheler, P. | Mangin, B. | Goffinet, B. | Roy, P Le | Boichard, D. | Elsen, J.M.
SUMMARY: A Bayesian approach to map Quantitative Trait Loci (QTL) is compared to the flanking markers regression method (asymptotically equivalent to the traditional Interval Mapping method) using simulated backcross data. The main part consists of a comparison of the properties for a one QTL model. The Bayesian approach gives less biases and more accurate estimates of the genetic effect and significance thresholds close to χ² quantiles when the number of individuals and markers become large. The behaviour of both approaches in the case of two linked QTL is mentioned.
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